|
KMID : 0358419940370040724
|
|
Korean Journal of Obstetrics and Gynecology
1994 Volume.37 No. 4 p.724 ~ p.730
|
|
|
Prognostic Significance of DNA Ploidy Patterns in Early Cancer of the Uterine Cervix
|
|
박은동
이영미/김원규/김흥열/장희경/허만하/김인선
|
|
|
Abstract
|
|
|
Prognostic value of flow cytometric DNA analysis was assessed for early cervical cancer patients (FIGO stage I & IIa) treated with radical abdominal hysterectomy and lymph node dissection.
Flow cytometry was performed on archival paraffin-embedded tumor tissues of 38 subjects. 8 patients received radiotherapy post-operatively because of the presence of lymph node metastasis at the time of initial surgery. 38 subjects were analized:
18
patients(47%) were categorized as DNA-aneuploidy and 20 (53%) patients were categorized as DNA-diploidy. 26(68%)patients were in FIGO stage IB, 12 (32%0 in IIA. 8(21%) patients were found to have lymphnode metastasis at the time of initial
surgery.
8(21%)patients recurred.
There is no significant correlation between DNA-ploidy patterns and stage, differentiation, cell type or mitosis. Although the results are not significant statistically, aneuploidy tended to be more frequently observed in association with lymph
node
metastasis and recurrence. Overall 5 year disease-free survival for diploid and aneuploid were 79.72% and 67.57%, respectively.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|